Time Zone – GMT-4 (America/New_York)
| 1 | MLS All-Stars | Liga MX All-Stars | 4 : 3 |
| Pl | W | D | L | Diff | Pts | |||
| 1 | Vancouver Whitecaps | 28 | 15 | 6 | 7 | 61:30 | 31 | 51 |
| 2 | St. Louis City | 28 | 14 | 8 | 6 | 54:38 | 16 | 50 |
| 3 | FC Dallas | 28 | 13 | 8 | 7 | 52:45 | 7 | 47 |
| 4 | San Jose Earthquakes | 28 | 13 | 7 | 8 | 50:40 | 10 | 46 |
| 5 | Houston Dynamo | 28 | 13 | 6 | 9 | 36:34 | 2 | 45 |
| 6 | Los Angeles FC | 29 | 11 | 9 | 9 | 44:31 | 13 | 42 |
| 7 | Seattle Sounders | 28 | 11 | 8 | 9 | 38:35 | 3 | 41 |
| 8 | Colorado Rapids | 28 | 11 | 4 | 13 | 39:39 | 0 | 37 |
| 9 | Los Angeles Galaxy | 29 | 9 | 9 | 11 | 39:50 | -11 | 36 |
| 10 | Portland Timbers | 28 | 9 | 6 | 13 | 51:54 | -3 | 33 |
| 11 | Real Salt Lake | 28 | 9 | 5 | 14 | 41:46 | -5 | 32 |
| 12 | San Diego FC | 28 | 8 | 8 | 12 | 48:51 | -3 | 32 |
| 13 | Austin FC | 28 | 7 | 10 | 11 | 36:51 | -15 | 31 |
| 14 | Minnesota United | 28 | 7 | 9 | 12 | 42:51 | -9 | 30 |
| 15 | Sporting Kansas City | 28 | 6 | 4 | 18 | 35:68 | -33 | 22 |
| Pl | W | D | L | Diff | Pts | |||
| 1 | Nashville SC ✔ | 28 | 19 | 6 | 3 | 59:22 | 37 | 63 |
| 2 | Inter Miami | 28 | 13 | 10 | 5 | 68:50 | 18 | 49 |
| 3 | Chicago Fire | 28 | 14 | 6 | 8 | 51:40 | 11 | 48 |
| 4 | New England Revolution | 28 | 14 | 4 | 10 | 45:39 | 6 | 46 |
| 5 | Charlotte | 28 | 13 | 7 | 8 | 50:40 | 10 | 46 |
| 6 | Philadelphia Union | 28 | 12 | 6 | 10 | 56:45 | 11 | 42 |
| 7 | Orlando City | 28 | 11 | 4 | 13 | 51:66 | -15 | 37 |
| 8 | New York Red Bulls | 28 | 10 | 6 | 12 | 38:52 | -14 | 36 |
| 9 | FC Cincinnati | 27 | 9 | 9 | 9 | 58:65 | -7 | 36 |
| 10 | New York City | 28 | 8 | 9 | 11 | 42:38 | 4 | 33 |
| 11 | Toronto FC | 28 | 7 | 11 | 10 | 41:52 | -11 | 32 |
| 12 | DC United | 27 | 6 | 12 | 9 | 34:46 | -12 | 30 |
| 13 | Columbus Crew | 28 | 8 | 5 | 15 | 41:46 | -5 | 29 |
| 14 | Atlanta Utd | 28 | 7 | 6 | 15 | 33:48 | -15 | 27 |
| 15 | CF Montreal | 28 | 6 | 6 | 16 | 35:56 | -21 | 24 |
| Pl | W | D | L | Diff | Pts | |||
| 1 | Houston Dynamo | 20 | 12 | 2 | 6 | 29:24 | 5 | 38 |
| 2 | Vancouver Whitecaps | 19 | 11 | 4 | 4 | 40:18 | 22 | 37 |
| 3 | Los Angeles FC | 21 | 10 | 4 | 7 | 35:21 | 14 | 34 |
| 4 | San Jose Earthquakes | 20 | 10 | 3 | 7 | 38:28 | 10 | 33 |
| 5 | FC Dallas | 20 | 9 | 6 | 5 | 38:29 | 9 | 33 |
| 6 | St. Louis City | 20 | 8 | 6 | 6 | 28:26 | 2 | 30 |
| 7 | Colorado Rapids | 20 | 9 | 1 | 10 | 30:25 | 5 | 28 |
| 8 | Real Salt Lake | 19 | 8 | 4 | 7 | 33:30 | 3 | 28 |
| 9 | Portland Timbers | 20 | 8 | 3 | 9 | 37:36 | 1 | 27 |
| 10 | Los Angeles Galaxy | 21 | 6 | 7 | 8 | 25:30 | -5 | 25 |
| 11 | Minnesota United | 20 | 6 | 7 | 7 | 22:28 | -6 | 25 |
| 12 | Seattle Sounders | 19 | 7 | 3 | 9 | 21:26 | -5 | 24 |
| 13 | San Diego FC | 20 | 6 | 6 | 8 | 34:32 | 2 | 24 |
| 14 | Austin FC | 20 | 5 | 5 | 10 | 25:39 | -14 | 20 |
| 15 | Sporting Kansas City | 20 | 4 | 3 | 13 | 19:49 | -30 | 15 |
| Pl | W | D | L | Diff | Pts | |||
| 1 | Nashville SC | 20 | 14 | 4 | 2 | 40:15 | 25 | 46 |
| 2 | Inter Miami | 20 | 11 | 6 | 3 | 48:38 | 10 | 39 |
| 3 | Chicago Fire | 19 | 11 | 2 | 6 | 36:25 | 11 | 35 |
| 4 | New England Revolution | 20 | 10 | 3 | 7 | 32:25 | 7 | 33 |
| 5 | FC Cincinnati | 20 | 8 | 6 | 6 | 48:46 | 2 | 30 |
| 6 | Charlotte | 20 | 8 | 5 | 7 | 35:31 | 4 | 29 |
| 7 | New York City | 20 | 7 | 5 | 8 | 34:29 | 5 | 26 |
| 8 | New York Red Bulls | 20 | 7 | 4 | 9 | 30:42 | -12 | 25 |
| 9 | DC United | 20 | 5 | 9 | 6 | 27:33 | -6 | 24 |
| 10 | Orlando City | 20 | 6 | 3 | 11 | 32:50 | -18 | 21 |
| 11 | Toronto FC | 20 | 4 | 9 | 7 | 29:36 | -7 | 21 |
| 12 | Columbus Crew | 20 | 5 | 5 | 10 | 28:33 | -5 | 20 |
| 13 | Philadelphia Union | 20 | 5 | 5 | 10 | 30:37 | -7 | 20 |
| 14 | CF Montreal | 20 | 5 | 5 | 10 | 27:37 | -10 | 20 |
| 15 | Atlanta Utd | 20 | 5 | 3 | 12 | 23:35 | -12 | 18 |
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